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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DOPEY2 All Species: 24.85
Human Site: T1406 Identified Species: 42.05
UniProt: Q9Y3R5 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y3R5 NP_005119.2 2298 258184 T1406 Q K R Y G L A T A H H G R A L
Chimpanzee Pan troglodytes XP_531552 2298 258112 T1406 Q K R Y G L A T A H H G R A L
Rhesus Macaque Macaca mulatta XP_001084653 2286 256620 T1394 Q K R Y G L A T A H H G R A L
Dog Lupus familis XP_544874 2297 257913 T1406 Q K R Y G L A T A E R G R A L
Cat Felis silvestris
Mouse Mus musculus Q3UHQ6 2295 257491 T1404 Q K R Y G L A T A D R G G R L
Rat Rattus norvegicus XP_001055500 2294 257490 T1403 Q K R Y G L A T A D R G G R V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512569 2247 251024 L1391 Q I W S E H P L Q L E L L K L
Chicken Gallus gallus XP_001232723 2283 257889 M1388 Q K R Y E L L M V G G V N H I
Frog Xenopus laevis Q642P2 2270 256829 S1380 Q K K Y E L M S A G G N R G I
Zebra Danio Brachydanio rerio NP_956904 817 86774
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster A1ZBE8 2599 291169 S1696 G L K G N T N S G S Y A E Q V
Honey Bee Apis mellifera XP_395999 2434 273219 E1551 K N A H K E N E E V F T F T E
Nematode Worm Caenorhab. elegans Q9XW10 2417 267134 Q1469 I I Q S V M N Q S F N N R T S
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q03921 1698 194669 T859 R T R K V F S T E L T S I K S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 94.8 89.9 N.A. 86.4 86.4 N.A. 73.9 75.2 69 21.9 N.A. 27.6 32.1 22.3 N.A.
Protein Similarity: 100 99.7 96 94.6 N.A. 92.4 92.5 N.A. 83 85.4 82 28.7 N.A. 47 53.2 40.9 N.A.
P-Site Identity: 100 100 100 86.6 N.A. 73.3 66.6 N.A. 13.3 33.3 40 0 N.A. 0 0 6.6 N.A.
P-Site Similarity: 100 100 100 86.6 N.A. 73.3 73.3 N.A. 13.3 40 60 0 N.A. 26.6 13.3 33.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20.5 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 37.8 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 0 0 0 43 0 50 0 0 8 0 29 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 15 0 0 0 0 0 % D
% Glu: 0 0 0 0 22 8 0 8 15 8 8 0 8 0 8 % E
% Phe: 0 0 0 0 0 8 0 0 0 8 8 0 8 0 0 % F
% Gly: 8 0 0 8 43 0 0 0 8 15 15 43 15 8 0 % G
% His: 0 0 0 8 0 8 0 0 0 22 22 0 0 8 0 % H
% Ile: 8 15 0 0 0 0 0 0 0 0 0 0 8 0 15 % I
% Lys: 8 58 15 8 8 0 0 0 0 0 0 0 0 15 0 % K
% Leu: 0 8 0 0 0 58 8 8 0 15 0 8 8 0 43 % L
% Met: 0 0 0 0 0 8 8 8 0 0 0 0 0 0 0 % M
% Asn: 0 8 0 0 8 0 22 0 0 0 8 15 8 0 0 % N
% Pro: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % P
% Gln: 65 0 8 0 0 0 0 8 8 0 0 0 0 8 0 % Q
% Arg: 8 0 58 0 0 0 0 0 0 0 22 0 43 15 0 % R
% Ser: 0 0 0 15 0 0 8 15 8 8 0 8 0 0 15 % S
% Thr: 0 8 0 0 0 8 0 50 0 0 8 8 0 15 0 % T
% Val: 0 0 0 0 15 0 0 0 8 8 0 8 0 0 15 % V
% Trp: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 58 0 0 0 0 0 0 8 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _